Genetic imprinting during impaired spermatogenesis
نویسندگان
چکیده
منابع مشابه
Differential histone modifications mark mouse imprinting control regions during spermatogenesis.
Only some imprinting control regions (ICRs) acquire their DNA methylation in the male germ line. These imprints are protected against the global demethylation of the sperm genome following fertilisation, and are maintained throughout development. We find that in somatic cells and tissues, DNA methylation at these ICRs is associated with histone H4-lysine-20 and H3-lysine-9 trimethylation. The u...
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The MUC1 mucin [also known as episialin, epithelial membrane antigen (EMA) or polymorphic epithelial mucin (PEM)] is a component of the mucosal glycocalyx, contributing to anti-adhesive and protective cell functions. MUC1 has been shown in a variety of epithelial cell types in the reproductive tracts of males and females, but this is the first report of its expression in human testis and non-ep...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2006
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gal040